| First Lady/Gentleman | President | Took office | Left office | |
|---|---|---|---|---|
| 1 | Fatmawati | Sukarno | August 18, 1945 | March 12, 1967 |
| 2 | Siti Hartinah | Suharto | March 12, 1967 | April 28, 1996 |
| 3 | Hasri Ainun | Bacharuddin Jusuf Habibie | May 21, 1998 | October 20, 1999 |
| 4 | Sinta Nuriyah | Abdurrahman Wahid | October 20, 1999 | July 23, 2001 |
| 5 | Taufiq Kiemas | Megawati Sukarnoputri | July 23, 2001 | October 20, 2004 |
| 6 | Kristiani Herawati | Susilo Bambang Yudhoyono | October 20, 2004 | Incumbent |